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Sitting for prolonged periods is associated with health complications – but you can counteract the risks of a sedentary life.

The immunotherpay can give children and adults three extra years before they need to use insulin.

Dr Hilary Cass says she is "absolutely convinced that more children will be harmed if we don't do the trial than if we do."

The presenter shared his "aggressive" cancer diagnosis on an episode of Clarkson's Farm earlier this week.